SS-31
Mitochondrial protection
Elamipretide — the mitochondrial bodyguard that binds cardiolipin.
Research chemical vendors can't legally label products with the real name, so SS-31 often appears under coded SKUs. If you're shopping and see any of these, it's the same compound:
- SS31
- Elamipretide
- MTP-131
Codes shown are for identification only. Always verify third-party COAs before purchase.
A four amino acid peptide that selectively binds cardiolipin in the inner mitochondrial membrane, stabilizing the electron transport chain and preventing the cytochrome c leak that drives apoptosis.
- Mitochondrial myopathies and primary mitochondrial disease
- Age related muscle weakness and 'sarcopenia'
- Heart failure with preserved ejection fraction (HFpEF)
Educational only · Not a vendor claim
Binds cardiolipin in the inner mitochondrial membrane, stabilizing the electron transport chain and reducing cytochrome c leak.
- Protects mitochondrial function
- Reduces cardiac apoptosis
- Improves muscle strength in mito disease
- Energy improvement over weeks
- Better exercise tolerance
- Strength gains in deficiency states
- Highly targeted mechanism
- Strong clinical trial pipeline
- Useful in primary mito disease
- Expensive
- Effects subtle in healthy users
- Daily injection needed
- Mild injection site reaction
- Rare GI upset
Educational summary · Not medical advice · Discuss with a qualified clinician
Typical timeline
General pattern for the Mitochondrial category. Individual response varies.
- Week 1Energy floor lifts. Fewer afternoon crashes. Workouts feel less taxing.
- Weeks 2–4Endurance and recovery both improve. Some users report better glucose control.
- Weeks 4–8Peak effect. Consider a break so mitochondrial adaptation is preserved, not blunted.
Pairs well with
Common combinations experienced users run alongside SS-31. Always add one peptide at a time so you can attribute effects and side effects.
Read the safety guide before stacking.
The reconstitution math
- 1Reconstitute the 10 mg vial with 2 mL of bacteriostatic water. Tilt — don't shake.
- 2Concentration becomes 5,000 mcg/mL (5 mg/mL).
- 3For a 1 mg dose, draw 0.200 mL — that's 20 units on a 1 mL insulin syringe.
- 4One vial gives you approximately 10 doses.
Reminder: 100 units on an insulin syringe = 1 mL. Always start at half the listed dose for the first week and rotate injection sites between arms, legs, abdomen, and glutes.
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