Six proven combinations, organized by outcome. Each stack lists the compounds, the weekly timing, and the cycle length. Read the safety guide before starting anything with more than one peptide.
Tirzepatide + Cagrilintide (single or separate injections)
Mon–Fri AM
5-Amino-1MQ oral, empty stomach
Sat/Sun
5-Amino-1MQ break; hydrate + protein target ≥1 g/lb LBM
Notes: Titrate GLP-1 dose over 4 weeks. Bloodwork at week 8 (lipids, HbA1c, lipase). If fat loss stalls at a tolerated Tirzepatide ceiling, see the advanced Retatrutide stack below.
Goal
Advanced Cutting (Retatrutide)
For experienced users who have already plateaued on a GLP-1. Retatrutide is a triple agonist (GLP-1 + GIP + glucagon), so it raises energy expenditure on top of appetite suppression. Stronger appetite blunting means lean mass and nutrition need active protection.
Retatrutide, starting low (e.g. 1–2 mg) and holding 4 weeks before any increase
Mon–Fri AM
5-Amino-1MQ oral, empty stomach
Daily
Protein ≥1 g/lb LBM, resistance training 3×/week, electrolytes
Notes: Investigational and less characterized than Tirzepatide — GI side effects and heart rate increases are more common. Do not run alongside another GLP-1. Add Cagrilintide only after you tolerate Retatrutide alone. Bloodwork at week 8.
Goal
Injury Recovery
The classic soft-tissue repair stack. BPC drives blood supply; TB-500 drives cell migration; GHK-Cu handles collagen and skin.
No more than 2× per week — flushing/nausea compound with over-use
Notes: PT-141 can raise blood pressure for 6+ hours. Skip if BP is uncontrolled.
Before you stack
Never introduce more than one new peptide at a time. Run each compound solo for at least a week before adding the next — otherwise you can't attribute results or side effects. Review the full safety guide andbeginner roadmap first.
