Sermorelin
GHRH analog
The original GHRH analog — gentle, well studied, FDA history.
Research chemical vendors can't legally label products with the real name, so Sermorelin often appears under coded SKUs. If you're shopping and see any of these, it's the same compound:
- Sermo
- GRF 1-29
Codes shown are for identification only. Always verify third-party COAs before purchase.
A truncated GHRH (1-29) that triggers the pituitary to release its own GH. The first such peptide to be widely prescribed, with decades of pediatric and anti aging clinic use.
- Restoring age related decline in GH and IGF-1
- Sleep depth and body composition
- Gentler than CJC-1295 or Tesamorelin; preferred starting GHRH for cautious users
Educational only · Not a vendor claim
Truncated GHRH(1-29) that stimulates pituitary GH release within physiologic limits.
- Restored GH/IGF-1 in aging adults
- Better sleep depth
- Subtle body composition improvement
- Gradual energy and recovery improvement
- Better sleep within weeks
- FDA history (was prescription)
- Gentle, well tolerated
- Preserves natural GH pulsatility
- Subtle results
- Daily injection required
- Slower than CJC/Tesamorelin
- Injection site redness
- Mild headache
- Rare flushing
Educational summary · Not medical advice · Discuss with a qualified clinician
Typical timeline
General pattern for the Muscle category. Individual response varies.
- Week 1Deeper sleep, vivid dreams, possible morning hand tingling — normal GH-axis signals.
- Weeks 2–4Recovery between sessions improves. Modest fullness in muscles from mild water retention.
- Weeks 4–8Body comp changes become visible. Fat drops slightly, muscle looks fuller. Bloodwork check recommended.
- Weeks 8+Cycle off for at least equal time to restore natural pulsatility. Track IGF-1 if running longer.
Pairs well with
Common combinations experienced users run alongside Sermorelin. Always add one peptide at a time so you can attribute effects and side effects.
Read the safety guide before stacking.
The reconstitution math
- 1Reconstitute the 10 mg vial with 2 mL of bacteriostatic water. Tilt — don't shake.
- 2Concentration becomes 5,000 mcg/mL (5 mg/mL).
- 3For a 375 mcg dose, draw 0.075 mL — that's 8 units on a 1 mL insulin syringe.
- 4One vial gives you approximately 26 doses.
Reminder: 100 units on an insulin syringe = 1 mL. Always start at half the listed dose for the first week and rotate injection sites between arms, legs, abdomen, and glutes.
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