Sermorelin
GHRH analog
The original GHRH analog — gentle, well studied, FDA history.
Also sold as
Research chemical vendors can't legally label products with the real name, so Sermorelin often appears under coded SKUs. If you're shopping and see any of these, it's the same compound:
- Sermo
- GRF 1-29
Codes shown are for identification only.
Your draw
What it actually is
A truncated GHRH (1-29) that triggers the pituitary to release its own GH. The first such peptide to be widely prescribed, with decades of pediatric and anti aging clinic use.
Why people use it
- Restoring age related decline in GH and IGF-1
- Sleep depth and body composition
- Gentler than CJC-1295 or Tesamorelin; preferred starting GHRH for cautious users
Educational only · Not a vendor claim
How it works
Truncated GHRH(1-29) that stimulates pituitary GH release within physiologic limits.
Health benefits
- Restored GH/IGF-1 in aging adults
- Better sleep depth
- Subtle body composition improvement
What you'll feel
- Gradual energy and recovery improvement
- Better sleep within weeks
Pros
- FDA history (was prescription)
- Gentle, well tolerated
- Preserves natural GH pulsatility
Cons
- Subtle results
- Daily injection required
- Slower than CJC/Tesamorelin
Side effects to know
- Injection site redness
- Mild headache
- Rare flushing
Best suited for
Educational summary · Not medical advice · Discuss with a qualified clinician
Typical timeline
General pattern for the Muscle category. Individual response varies.
- Week 1Deeper sleep, vivid dreams, possible morning hand tingling — normal GH-axis signals.
- Weeks 2–4Recovery between sessions improves. Modest fullness in muscles from mild water retention.
- Weeks 4–8Body comp changes become visible. Fat drops slightly, muscle looks fuller. Bloodwork check recommended.
- Weeks 8+Cycle off for at least equal time to restore natural pulsatility. Track IGF-1 if running longer.
Pairs well with
Common combinations experienced users run alongside Sermorelin. Always add one peptide at a time so you can attribute effects and side effects.
Read the safety guide before stacking.
The reconstitution math
- 1Reconstitute the 10 mg vial with 2 mL of bacteriostatic water. Tilt — don't shake.
- 2Concentration becomes 5,000 mcg/mL (5 mg/mL).
- 3For a 375 mcg dose, draw 0.075 mL — that's 8 units on a 1 mL insulin syringe.
- 4One vial gives you approximately 26 doses.
Reminder: 100 units on an insulin syringe = 1 mL. Always start at half the listed dose for the first week and rotate injection sites between arms, legs, abdomen, and glutes.
Dose logging is available for signed-in users. Track today's dose and notes for Sermorelin.
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Mixing ratios, units to draw and storage basics — one page, no strings.
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Keep going from here
Everything on the site that connects to Sermorelin: comparable compounds, the exact math for this vial, and the tools to run the cycle.
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Tools for this protocol
Prefilled with 10 mg, 2 mL BAC water, and a 375 mcg dose.
Printable units-to-micrograms lookup for every common vial and water volume.
Add Sermorelin to a protocol with schedule, dosing, and a shopping list.
Log each dose so you can tie effects and side effects to real dates.
Put Sermorelin next to two other peptides on dosing and goals.
The full muscle hub: peptides, stacks, and guides in one place.