MGF
Local muscle growth
Mechano growth factor — the local muscle building splice of IGF-1.
Research chemical vendors can't legally label products with the real name, so MGF often appears under coded SKUs. If you're shopping and see any of these, it's the same compound:
- MGF
- Mechano Growth Factor
Codes shown are for identification only. Always verify third-party COAs before purchase.
An alternative splice variant of IGF-1 expressed in muscle in response to mechanical load. It activates satellite cells (the stem cells of skeletal muscle) and drives new myonuclei.
- Localized muscle growth post workout — inject directly into the muscle just trained
- Recovery from focal muscle injury
- Use is intentionally short (4 on, 4 off) because chronic dosing downregulates the receptor
Educational only · Not a vendor claim
Local IGF-1 splice variant that activates satellite cells and adds myonuclei to trained muscle.
- Localized muscle growth
- Faster recovery from focal injury
- Satellite cell activation
- Targeted muscle fullness
- Faster local recovery
- Strength gains in trained group
- Site specific action
- Short cycles (4 weeks)
- Powerful local effect
- Requires intramuscular injection
- Receptor downregulates fast
- Not for systemic growth
- Local soreness
- Mild hypoglycemia post injection
- Injection site lumps
Educational summary · Not medical advice · Discuss with a qualified clinician
Typical timeline
General pattern for the Muscle category. Individual response varies.
- Week 1Deeper sleep, vivid dreams, possible morning hand tingling — normal GH-axis signals.
- Weeks 2–4Recovery between sessions improves. Modest fullness in muscles from mild water retention.
- Weeks 4–8Body comp changes become visible. Fat drops slightly, muscle looks fuller. Bloodwork check recommended.
- Weeks 8+Cycle off for at least equal time to restore natural pulsatility. Track IGF-1 if running longer.
Pairs well with
Common combinations experienced users run alongside MGF. Always add one peptide at a time so you can attribute effects and side effects.
Read the safety guide before stacking.
The reconstitution math
- 1Reconstitute the 5 mg vial with 5 mL of bacteriostatic water. Tilt — don't shake.
- 2Concentration becomes 1,000 mcg/mL (1 mg/mL).
- 3For a 150 mcg dose, draw 0.150 mL — that's 15 units on a 1 mL insulin syringe.
- 4One vial gives you approximately 33 doses.
Reminder: 100 units on an insulin syringe = 1 mL. Always start at half the listed dose for the first week and rotate injection sites between arms, legs, abdomen, and glutes.
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