MGF
Local muscle growth
Mechano growth factor — the local muscle building splice of IGF-1.
Also sold as
Research chemical vendors can't legally label products with the real name, so MGF often appears under coded SKUs. If you're shopping and see any of these, it's the same compound:
- MGF
- Mechano Growth Factor
Codes shown are for identification only.
Your draw
What it actually is
An alternative splice variant of IGF-1 expressed in muscle in response to mechanical load. It activates satellite cells (the stem cells of skeletal muscle) and drives new myonuclei.
Why people use it
- Localized muscle growth post workout — inject directly into the muscle just trained
- Recovery from focal muscle injury
- Use is intentionally short (4 on, 4 off) because chronic dosing downregulates the receptor
Educational only · Not a vendor claim
How it works
Local IGF-1 splice variant that activates satellite cells and adds myonuclei to trained muscle.
Health benefits
- Localized muscle growth
- Faster recovery from focal injury
- Satellite cell activation
What you'll feel
- Targeted muscle fullness
- Faster local recovery
- Strength gains in trained group
Pros
- Site specific action
- Short cycles (4 weeks)
- Powerful local effect
Cons
- Requires intramuscular injection
- Receptor downregulates fast
- Not for systemic growth
Side effects to know
- Local soreness
- Mild hypoglycemia post injection
- Injection site lumps
Best suited for
Educational summary · Not medical advice · Discuss with a qualified clinician
Typical timeline
General pattern for the Muscle category. Individual response varies.
- Week 1Deeper sleep, vivid dreams, possible morning hand tingling — normal GH-axis signals.
- Weeks 2–4Recovery between sessions improves. Modest fullness in muscles from mild water retention.
- Weeks 4–8Body comp changes become visible. Fat drops slightly, muscle looks fuller. Bloodwork check recommended.
- Weeks 8+Cycle off for at least equal time to restore natural pulsatility. Track IGF-1 if running longer.
Pairs well with
Common combinations experienced users run alongside MGF. Always add one peptide at a time so you can attribute effects and side effects.
Read the safety guide before stacking.
The reconstitution math
- 1Reconstitute the 5 mg vial with 5 mL of bacteriostatic water. Tilt — don't shake.
- 2Concentration becomes 1,000 mcg/mL (1 mg/mL).
- 3For a 150 mcg dose, draw 0.150 mL — that's 15 units on a 1 mL insulin syringe.
- 4One vial gives you approximately 33 doses.
Reminder: 100 units on an insulin syringe = 1 mL. Always start at half the listed dose for the first week and rotate injection sites between arms, legs, abdomen, and glutes.
Dose logging is available for signed-in users. Track today's dose and notes for MGF.
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Mixing ratios, units to draw and storage basics — one page, no strings.
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Keep going from here
Everything on the site that connects to MGF: comparable compounds, the exact math for this vial, and the tools to run the cycle.
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Tools for this protocol
Prefilled with 5 mg, 5 mL BAC water, and a 150 mcg dose.
Printable units-to-micrograms lookup for every common vial and water volume.
Add MGF to a protocol with schedule, dosing, and a shopping list.
Log each dose so you can tie effects and side effects to real dates.
Put MGF next to two other peptides on dosing and goals.
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