PT-141
Libido
Centrally acting libido — bypass the vascular pathway of Viagra and Cialis entirely.
Also sold as
Research chemical vendors can't legally label products with the real name, so PT-141 often appears under coded SKUs. If you're shopping and see any of these, it's the same compound:
- PT141
- Branch-P141· Branch Peptides
- Bremelanotide
- Vyleesi (Rx)
Codes shown are for identification only.
Your draw
What it actually is
Bremelanotide is a melanocortin receptor agonist that acts on MC4R in the central nervous system. Unlike PDE5 inhibitors, it doesn't work on blood vessels — it works on desire itself.
Why people use it
- Low libido in men and women (FDA approved as Vyleesi for HSDD in women)
- Cases where Viagra/Cialis fail because the issue is desire, not vasculature
- Onset 30–60 minutes, lasts hours
Educational only · Not a vendor claim
How it works
Melanocortin receptor agonist acting centrally on MC4R — drives sexual desire, not blood flow.
Health benefits
- Increased libido (M and F)
- Works when PDE5 inhibitors fail
- Acts on desire, not just function
What you'll feel
- Onset 30–60 min
- Lasts 4–8 hours
- Stronger arousal and desire
Pros
- Works centrally — different mechanism from Viagra
- FDA approved for women (Vyleesi)
- Useful when vascular drugs fail
Cons
- Nausea common at higher doses
- BP elevation possible
- Mole darkening with chronic use
Side effects to know
- Nausea
- Facial flushing
- Headache
- Transient BP increase
Best suited for
Educational summary · Not medical advice · Discuss with a qualified clinician
Typical timeline
General pattern for the Sexual Health category. Individual response varies.
- Acute (PT-141, Oxytocin)Effect within 30–90 minutes. Facial flushing and slight nausea are common early on.
- Weeks 1–4 (Gonadorelin, HCG)Testicular volume returns on TRT. Fertility markers respond over 8–12 weeks.
Pairs well with
Common combinations experienced users run alongside PT-141. Always add one peptide at a time so you can attribute effects and side effects.
Read the safety guide before stacking.
The reconstitution math
- 1Reconstitute the 10 mg vial with 2 mL of bacteriostatic water. Tilt — don't shake.
- 2Concentration becomes 5,000 mcg/mL (5 mg/mL).
- 3For a 1 mg dose, draw 0.200 mL — that's 20 units on a 1 mL insulin syringe.
- 4One vial gives you approximately 10 doses.
Reminder: 100 units on an insulin syringe = 1 mL. Always start at half the listed dose for the first week and rotate injection sites between arms, legs, abdomen, and glutes.
Dose logging is available for signed in users. Track today's dose and notes for PT-141.
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Mixing ratios, units to draw and storage basics — one page, no strings.
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Keep going from here
Everything on the site that connects to PT-141: comparable compounds, the exact math for this vial, and the tools to run the cycle.
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Tools for this protocol
Prefilled with 10 mg, 2 mL BAC water, and a 1 mg dose.
Printable units-to-micrograms lookup for every common vial and water volume.
Add PT-141 to a protocol with schedule, dosing, and a shopping list.
Log each dose so you can tie effects and side effects to real dates.
Put PT-141 next to two other peptides on dosing and goals.